基于深度神经网络的表面划痕识别方法

为实现亮度不均的复杂纹理背景下表面划痕的鲁棒、精确、实时识别，提出一种基于深度神经网络的表面划痕识别方法。用于表面划痕识别的深度神经网络由风格迁移网络和聚焦卷积神经网络（CNN）构成，其中风格迁移网络针对亮度不均的复杂背景下的表面划痕进行预处理，风格迁移网络包括前馈转换网络和损失网络，首先通过损失网络提取亮度均匀模板的风格特征和检测图像的知觉特征，对前馈转换网络进行离线训练，获取网络最优参数值，最终使风格迁移网络生成亮度均匀且风格一致的图像，然后，利用所提出的基于聚焦结构的聚焦卷积神经网络对生成图像中的划痕特征进行提取并识别。以光照变化的金属表面为例，进行划痕识别实验，实验结果表明：与需要人工设计特征的传统图像处理方法及传统深度卷积神经网络相比，划痕漏报率低至8.54%，并且收敛速度更快，收敛曲线更加平滑，在不同的深度模型下均可取得较好的检测效果，准确率提升2%左右。风格迁移网络能够保留完整划痕特征的同时有效解决亮度不均的问题，从而提高划痕识别精度；同时聚焦卷积神经网络能够实现对划痕的鲁棒、精确、实时识别，大幅度降低划痕漏报率和误报率。     

Expression of Main Toll-Like Receptors in Patients with Different Types of Colorectal Polyps and Their Relationship with Gut Microbiota

Abnormal activation of Toll-like receptor (TLRs) signaling can result in colon cancer development. The aim of this study was to investigate the expression of important TLRs in different histological types of colorectal polyps and evaluate their relationship with intestinal microbiota. The expression levels of TLR2, 3, 4, and 5 were analyzed in intestinal biopsy specimens of 21 hyperplastic polyp (HP), 16 sessile serrated adenoma (SSA), 29 tubular adenoma (TA), 21 villous/tubulovillous (VP/TVP) cases, and 31 normal controls. In addition, selected gut bacteria including Streptococcus bovis, Enterococcus faecalis, Enterotoxigenic Bacteroides fragilis (ETBF), Fusobacterium nucleatum, Porphyromonas spp., Lactobacillus spp., Roseburia spp., and Bifidobacterium spp. were quantified in fecal samples using absolute qRT PCR, and, finally, the association between TLRs and these gut microbiota- was evaluated by Spearman’s correlation coefficient. Higher expression of TLR2 and TLR4 in VP/TVP and TA, and lower expression levels of TLR3 and TLR5 in all type of polyps were observed. The differences in TLR expression patterns was not only dependent on the histology, location, size, and dysplasia grade of polyps but also related to the intestinal microbiota patterns. TLR2 and TLR4 expression was directly associated with the F. nucleatum, E. faecalis, S. bovis, Porphyromonas, and inversely to Bifidobacterium, Lactobacillus, and Roseburia quantity. Furthermore, TLR3 and TLR5 expression was directly associated with Bifidobacterium, Roseburia, and Lactobacillus quantity. Our results suggest a possible critical role of TLRs during colorectal polyp progression. An abnormal regulation of TLRs in relation to gut microbial quantity may contribute to carcinogenesis.     

基于DRGAN和支持向量机的合成孔径雷达图像目标识别

为解决SAR图像目标识别中样本缺乏和方位角敏感问题,提出了一种基于DRGAN和SVM的SAR图像目标识别算法。首先,采用多尺度分形特征对SAR图像进行增强,经过分割得到目标二值图像,基于Hu二阶矩估计目标的方位角。然后对估计得到的目标方位角进行量化编码,结合原始图像作为输入,对设计的DRGAN模型参数进行训练与优化。由于DRGAN中的深度生成模型将目标姿态与外观表示进行解耦设计,故可利用该模型将SAR图像样本变换到同一方位角区间。基于变换后的训练样本分别提取归一化灰度特征,利用SVM训练分类器。采用MSTAR数据集在多个不同操作条件下对提出的算法进行测试,实验结果表明,在带变体的标准操作条件下,能够达到97.97%的分类精度,优于部分基于CNN模型的分类精度,在4种扩展操作条件下的分类精度分别为97.83%,91.77%,97.11%和97.04%,均优于传统方法的分类精度。在SAR图像目标方位角估计存在一定误差的情况下,训练得到的GAN模型作为SAR图像目标旋转估计器,能够使得在不进行复杂样本预处理的前提下,仍然取得较高的SAR图像目标识别精度。     

基于目标跟踪的变电站隔离开关状态图像识别方法

为解决变电站中隔离开关状态的自动识别问题，提出了基于目标跟踪的开关分合状态图像识别方法。首先，基于隔离开关开合过程的动态视频，通过 Ｌａｓｓｏ正则化稀疏表示的目标跟踪模型对隔离开关运动轨迹进行识别；其次，利用隔离开关２个闸刀之间的距离自动识别算法获得开关的分合状态。实测结果表明，该方法可快速跟踪开关运行轨迹，实时对变电站中隔离开关状态进行准确识别。     

Gait event detection algorithm based on smart insoles

Gait analysis is an effective clinical tool across a wide range of applications. Recently, inertial measurement units have been extensively utilized for gait analysis. Effective gait analyses require good estimates of heel‐strike and toe‐off events. Previous studies have focused on the effective device position and type of triaxis direction to detect gait events. This study proposes an effective heel‐strike and toe‐off detection algorithm using a smart insole with inertial measurement units. This method detects heel‐strike and toe‐off events through a time‐frequency analysis by limiting the range. To assess its performance, gait data for seven healthy male subjects during walking and running were acquired. The proposed heel‐strike and toe‐off detection algorithm yielded the largest error of 0.03 seconds for running toe‐off events, and an average of 0–0.01 seconds for other gait tests. Novel gait analyses could be conducted without suffering from space limitations because gait parameters such as the cadence, stance phase time, swing phase time, single‐support time, and double‐support time can all be estimated using the proposed heel‐strike and toe‐off detection algorithm.     

小尺度交通信号灯的检测与状态识别

交通信号灯识别包括检测和状态识别，在智能交通系统中发挥重要作用。基于YOLOv3算法提出了一种交通信号灯检测与状态识别模型。针对交通信号灯相较于交通场景中其他目标具有尺度小的特性进行了算法的设计：降低骨干网络的下采样倍率以增加小尺度目标的特征描述能力；通过增大特征图的尺度来改进多尺度特征融合；引入广义交并比作为检测任务的损失函数来改进目标边界框的回归效果。同时，根据交通信号灯本身的特性，使用颜色和形状约束的方法对信号灯进行状态识别和类别验证。最后在公开的Bosch交通信号灯数据集上和实际的城区道路进行了实验验证。实验结果表明，所提出的算法能够提升交通信号灯识别的精度和召回率，识别准确率可以达到90%左右。     

基于卷积神经网络的表情识别

在传统静态表情识别研究基础上,提出一种简单的人脸裁剪方法,再用浅层卷积神经网络进一步提取特征并进行表情识别。以CK+和JAFFE为实验数据集,进行预处理效果对比实验、数据增强实验、单种表情识别实验和跨数据集六分类实验。结果表明,针对数据量较少的情况,提出的表情识别方法效果明显且鲁棒性更优。     

基于GFU和分层LSTM的组群行为识别研究方法

提出一种以"关键人物"为核心，使用门控融合单元（GFU，Gated Fusion Unit）进行特征融合的组群行为识别框架，旨在解决两个问题：①组群行为信息冗余，重点关注关键人物行为特征，忽略无关人员对组群行为的影响；②组群内部交互行为复杂，使用GFU有效融合以关键人物为核心的交互特征，再通过LSTM时序建模成为表征能力更强的组群特征.最终，通过softmax分类器进行组群行为类别分类.该算法在排球数据集上取得了86.7%的平均识别率.     

Chemical-Shift Perturbations Reflect Bile Acid Binding to Norovirus Coat Protein: Recognition Comes in Different Flavors

Bile acids have been reported as important cofactors promoting human and murine norovirus (NoV) infections in cell culture. The underlying mechanisms are not resolved. Through the use of chemical shift perturbation (CSP) NMR experiments, we identified a low-affinity bile acid binding site of a human GII.4 NoV strain. Long-timescale MD simulations reveal the formation of a ligand-accessible binding pocket of flexible shape, allowing the formation of stable viral coat protein–bile acid complexes in agreement with experimental CSP data. CSP NMR experiments also show that this mode of bile acid binding has a minor influence on the binding of histo-blood group antigens and vice versa. STD NMR experiments probing the binding of bile acids to virus-like particles of seven different strains suggest that low-affinity bile acid binding is a common feature of human NoV and should therefore be important for understanding the role of bile acids as cofactors in NoV infection.